SEC Form 4

FORM 4		UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940	OMB APPROVAL OMB Number: 3235-0287 Estimated average burden hours per response: 0.5
	Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

1. Name and Address of Reporting Person* Vida Ventures GP III, L.L.C. (Last) (First) (Middle) 40 BROAD STREET, SUITE 201 (Street) BOSTON MA 02109 (City) (State) (Zip)	2. Issuer Name and Ticker or Trading Symbol Vigil Neuroscience, Inc. [ VIGL ]	5. Relationship of Reporting Person(s) to Issuer (Check all applicable) Director X 10% Owner Officer (give title below) Other (specify below)
	3. Date of Earliest Transaction (Month/Day/Year) 01/11/2022
	4. If Amendment, Date of Original Filed (Month/Day/Year)	6. Individual or Joint/Group Filing (Check Applicable Line) Form filed by One Reporting Person X Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3)	2. Transaction Date (Month/Day/Year)	2A. Deemed Execution Date, if any (Month/Day/Year)	3. Transaction Code (Instr. 8)		4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5)			5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4)	6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	7. Nature of Indirect Beneficial Ownership (Instr. 4)
			Code	V	Amount	(A) or (D)	Price
Common Stock	01/11/2022		C		3,333,245	A	(1)	3,333,245	I	By Vida Ventures III, L.P.(2)
Common Stock	01/11/2022		C		7,684	A	(1)	7,684	I	By Vida Ventures III-A, L.P.(3)
Common Stock	01/11/2022		P		1,671,148	A	$14(4)	5,004,393	I	By Vida Ventures III, L.P.(2)
Common Stock	01/11/2022		P		3,852	A	$14(5)	11,536	I	By Vida Ventures III-A, L.P.(3)

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Transaction Date (Month/Day/Year)	3A. Deemed Execution Date, if any (Month/Day/Year)	4. Transaction Code (Instr. 8)		5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5)		6. Date Exercisable and Expiration Date (Month/Day/Year)		7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4)		8. Price of Derivative Security (Instr. 5)	9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)	10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)
				Code	V	(A)	(D)	Date Exercisable	Expiration Date	Title	Amount or Number of Shares
Series B Preferred Stock	(1)	01/11/2022		C			9,243,756	(1)	(1)	Common Stock	3,333,245	$0.00	0	I	By Vida Ventures III, L.P.(2)
Series B Preferred Stock	(1)	01/11/2022		C			21,310	(1)	(1)	Common Stock	7,684	$0.00	0	I	By Vida Ventures III-A, L.P.(3)

1. Name and Address of Reporting Person* Vida Ventures GP III, L.L.C. (Last) (First) (Middle) 40 BROAD STREET, SUITE 201 (Street) BOSTON MA 02109 (City) (State) (Zip)

1. Name and Address of Reporting Person* Vida Ventures III, L.P. (Last) (First) (Middle) 40 BROAD STREET, SUITE 201 (Street) BOSTON MA 02109 (City) (State) (Zip)

1. Name and Address of Reporting Person* Vida Ventures III-A, L.P. (Last) (First) (Middle) 40 BROAD STREET, SUITE 201 (Street) BOSTON MA 02109 (City) (State) (Zip)

Explanation of Responses:

1. Each share of Series B Preferred Stock automatically converted into shares of the Issuer's common stock, par value $0.0001 per share ("Common Stock") on a one-for-2.7732 basis upon the closing of the Issuer's initial public offering on January 11, 2022 and had no expiration date.

2. The shares are held directly by Vida Ventures III, L.P. ("Vida III"). Vida Ventures GP III, L.L.C.("Vida III GP") is the general partner of Vida III. Vida III GP disclaims beneficial ownership of the securities held of record by Vida III, and this report shall not be deemed an admission that they are the beneficial owner of such securities for purposes of Section 16 or for any other purpose, except to the extent of their pecuniary interest therein, if any.

3. The shares are held directly by Vida Ventures III-A, L.P. ("Vida III-A"). Vida III GP is the general partner of Vida III-A. Vida III GP disclaims beneficial ownership of the securities held of record by Vida III-A, and this report shall not be deemed an admission that they are the beneficial owner of such securities for purposes of Section 16 or for any other purpose, except to the extent of their pecuniary interest therein, if any.

4. On January 11, 2022, Vida III purchased 1,671,148 shares of Common Stock of the Issuer at a price of $14.00 per share pursuant to an underwritten public offering.

5. On January 11, 2022, Vida III-A purchased 3,852 shares of Common Stock of the Issuer at a price of $14.00 per share pursuant to an underwritten public offering.

Remarks:

	VIDA VENTURES GP III, L.L.C., By: /s/ Stefan Vitorovic, its Managing Member	01/11/2022
	VIDA VENTURES III, L.P., By: Vida Ventures GP III, L.L.C., its general partner, By: /s/ Stefan Vitorovic, its Managing Member	01/11/2022
	VIDA VENTURES III-A, L.P., By: Vida Ventures GP III, L.L.C., its general partner, By: /s/ Stefan Vitorovic, its Managing Member	01/11/2022
	** Signature of Reporting Person	Date
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